Research rigor
The criteria used
Reflects the level of scientific quality of the research, considering the methodology used, such as meta-analysis, randomized studies, cohort studies, case-control studies, and others. The higher the rigor, the more reliable the conclusions.
Research method
Systematic review and meta-analysis
A systematic review evaluates and compiles studies on a treatment. A meta-analysis combines their results to estimate the effect more precisely.
Randomized clinical trial
A study that evaluates the efficacy of an intervention, with participants randomly assigned to groups with or without treatment.
Observational cohort studies
An observational study in which patients are followed over time without interference from researchers.
Case-control study
Compares people with and without migraine, analyzing past exposures to identify possible associated factors.
It does not prove causation but helps generate hypotheses about treatments or triggers.
Quantitative study
Investigates treatments using numerical data, such as attack frequency, pain intensity, or response to medication. It allows measurement and comparison of outcomes between groups, generating objective evidence on the efficacy of interventions.
Case series or consecutive study
Follows a group of patients with migraine who receive the same treatment, describing their outcomes over time. There is no comparison group, but it helps observe patterns and generate initial hypotheses about efficacy or effects.
Expert opinion
The professional expresses their opinion regarding the treatment without conducting tests on groups or patients with the studied condition.